Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13939683 | 0.92 | PCSK9 (0.55) | MAOBDPP4L3MBTL1ALDH1A1TSHR | |
| SCHEMBL13939679 | 0.87 | PCSK9 (0.56) | CYP3A4CYP2C19DPP4L3MBTL1KMT2A | |
| SCHEMBL13938272 | 0.87 | MAOB (0.54) | MAOBCYP3A4CYP2C19DPP4L3MBTL1 | |
| SCHEMBL13939665 | 0.86 | DPP4 (0.51) | DPP4L3MBTL1KMT2AALDH1A1TSHR | |
| SCHEMBL13939649 | 0.85 | SMN1; SMN2 (0.58) | MAOBCYP3A4CYP2C19DPP4KMT2A | |
| SCHEMBL13939514 | 0.83 | DPP4 (0.49) | DPP4L3MBTL1KMT2AALDH1A1TSHR | |
| SCHEMBL13938894 | 0.82 | MAOB (0.55) | MAOBCYP3A4CYP2C19DPP4L3MBTL1 | |
| SCHEMBL13939684 | 0.82 | ALDH1A1 (0.53) | CYP3A4CYP2C19DPP4L3MBTL1KMT2A | |
| SCHEMBL13939669 | 0.81 | DPP4 (0.52) | DPP4L3MBTL1KMT2AALDH1A1TSHR | |
| SCHEMBL13938451 | 0.81 | MAOB (0.68) | MAOBCYP3A4CYP2C19DPP4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495004-B2 | Purine derivatives as liver X receptor agonists | GLAXO GROUP LIMITED (GB) | 2009-02-24 | — | — | US | disclosed |