SCHEMBL13939727

SCHEMBL13939727

Cc1noc(C)c1Cn1cc(N(C=O)C(=O)C(N)CC(=O)O)cn1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TAS2R8 Q9NYW2 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12062423 0.90 TAS2R8 (0.54) TAS2R8
SCHEMBL12292121 0.87 TAS2R8 (0.58) TAS2R8
SCHEMBL12062573 0.82 TAS2R8 (0.51) TAS2R8
SCHEMBL27811247 0.74 TAS2R8 (0.57) TAS2R8
SCHEMBL1278920 0.71 TAS2R8 (1.00) TAS2R8
SCHEMBL1278918 0.71 TAS2R8 (1.00) TAS2R8
SCHEMBL935659 0.69 TAS2R8 (0.62) TAS2R8
SCHEMBL12062569 0.69 TAS2R8 (0.61) TAS2R8
SCHEMBL21972771 0.69 TAS2R8 (0.51) TAS2R8
SCHEMBL12062566 0.69 TAS2R8 (0.56) TAS2R8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009025793-A2 HUMAN T2R BITTERNESS RECEPTORS AND USES THEREOF SENOMYX, INC. (US) 2009-02-26 — — WO disclosed
Send feedback