Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 20/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12062608 | 0.76 | TAS2R8 (0.59) | TAS2R8 | |
| SCHEMBL17001608 | 0.73 | TAS2R8 (0.64) | TAS2R8 | |
| SCHEMBL12062573 | 0.71 | TAS2R8 (0.51) | TAS2R8 | |
| SCHEMBL12062423 | 0.71 | TAS2R8 (0.54) | TAS2R8 | |
| SCHEMBL12062569 | 0.70 | TAS2R8 (0.61) | TAS2R8 | |
| SCHEMBL12062566 | 0.70 | TAS2R8 (0.56) | TAS2R8 | |
| SCHEMBL13939727 | 0.69 | TAS2R8 (0.55) | TAS2R8 | |
| SCHEMBL1278874 | 0.68 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL24857477 | 0.67 | TAS2R8 (0.79) | TAS2R8TAS2R14 | |
| SCHEMBL12292121 | 0.67 | TAS2R8 (0.58) | TAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3104712-B1 | IMPROVED PROCESS FOR THE SYNTHESIS OF SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES | FIRMENICH INCORPORATED (US) | 2020-05-06 | — | — | EP | disclosed |