Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 20/20 | 0.66 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13939288 | 0.91 | TAS2R8 (0.79) | TAS2R8TAS2R14 | |
| SCHEMBL11924494 | 0.88 | TAS2R8 (0.82) | TAS2R8TAS2R14 | |
| SCHEMBL13940418 | 0.83 | TAS2R8 (0.82) | TAS2R8TAS2R14 | |
| SCHEMBL1279238 | 0.80 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL13938941 | 0.80 | TAS2R8 (0.86) | TAS2R8TAS2R14 | |
| SCHEMBL1279536 | 0.79 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL13940035 | 0.79 | TAS2R8 (0.85) | TAS2R8TAS2R14 | |
| SCHEMBL16716544 | 0.78 | TAS2R8 (0.78) | TAS2R8 | |
| SCHEMBL1279156 | 0.77 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1278978 | 0.77 | TAS2R8 (1.00) | TAS2R8TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009025793-A2 | HUMAN T2R BITTERNESS RECEPTORS AND USES THEREOF | SENOMYX, INC. (US) | 2009-02-26 | — | — | WO | disclosed |