SCHEMBL1279156

SCHEMBL1279156

Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3cccc(O)c3)C2=O)cn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TAS2R8 Q9NYW2 20/20 1.00
▸ TAS2R14 Q9NYV8 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1278797 0.92 TAS2R8 (1.00) TAS2R8TAS2R14
SCHEMBL1279313 0.91 TAS2R8 (1.00) TAS2R8TAS2R14
SCHEMBL18351063 0.90 TAS2R8 (0.86) TAS2R8TAS2R14
SCHEMBL1279709 0.90 TAS2R8 (1.00) TAS2R8TAS2R14
SCHEMBL1279276 0.89 TAS2R8 (1.00) TAS2R8TAS2R14
SCHEMBL1279635 0.89 TAS2R8 (0.85) TAS2R8TAS2R14
SCHEMBL11924099 0.89 TAS2R8 (0.85) TAS2R8TAS2R14
SCHEMBL1279536 0.89 TAS2R8 (1.00) TAS2R8TAS2R14
SCHEMBL1278762 0.89 TAS2R8 (1.00) TAS2R8TAS2R14
SCHEMBL18351059 0.89 TAS2R8 (0.89) TAS2R8TAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12144365-B2 Emulsions and derivatives for infusing hydrophobic active agents into an edible product VERTOSA INC. (US) 2024-11-19 — — US claimed
CN-113543652-B Taste masking formulations for ketone body compounds 神经活力投资公司 2024-07-05 — — CN claimed
CN-118102892-A Composition comprising a nutrient and a taste modifier 弗门尼舍有限公司 2024-05-28 — — CN claimed
US-11801209-B2 Cooling and flavor boosting compositions FIRMENICH SA (CH) 2023-10-31 — — US claimed
CN-111032003-B Cooling and flavor enhancing compositions 弗门尼舍有限公司 2023-03-17 — — CN claimed
EP-3658109-B1 COOLING AND FLAVOR BOOSTING COMPOSITIONS FIRMENICH & CIE (CH) 2022-12-07 — — EP claimed
US-20200306156-A1 COOLING AND FLAVOR BOOSTING COMPOSITIONS FIRMENICH SA (CH) 2020-10-01 — — US claimed
EP-3658109-A1 COOLING AND FLAVOR BOOSTING COMPOSITIONS Firmenich SA (CH) 2020-06-03 — — EP claimed
CN-111032003-A Cooling and flavor enhancing compositions 弗门尼舍有限公司 2020-04-17 — — CN claimed
CN-122028804-A Flavanone compounds and their use as flavor modifiers 弗门尼舍有限公司 2026-05-12 — — CN disclosed
EP-4084620-B1 USE OF A STARCH MIXTURE IN A DAIRY PRODUCT ROQUETTE FRERES (FR) 2026-03-11 — — EP disclosed
EP-4661689-A1 MICROPARTICLES CONTAINING ALGAL PROTEINS AND USES THEREOF Firmenich SA (CH) 2025-12-17 — — EP disclosed
US-20250344734-A1 UNSATURATED FATTY ACIDS AND THEIR USE TO MODIFY TASTE FIRMENICH INCORPORATED (US) 2025-11-13 — — US disclosed
US-20250275559-A1 SATURATED FATTY ACIDS AND THEIR USE TO MODIFY TASTE FIRMENICH INCORPORATED (US) 2025-09-04 — — US disclosed
EP-2195656-A2 HUMAN T2R BITTERNESS RECEPTORS AND USES THEREOF Senomyx, Inc. (US) 2010-06-16 — — EP disclosed
US-20090274632-A1 Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in composition and use thereof SENOMYX, INC. (US) 2009-11-05 — — US disclosed
US-20090274632-A1 Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in composition and use thereof SENOMYX, INC. (US) 2009-11-05 — — US disclosed
US-20090274632-A1 Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in composition and use thereof SENOMYX, INC. (US) 2009-11-05 — — US disclosed
WO-2009025793-A2 HUMAN T2R BITTERNESS RECEPTORS AND USES THEREOF SENOMYX, INC. (US) 2009-02-26 — — WO disclosed
WO-2009025793-A2 HUMAN T2R BITTERNESS RECEPTORS AND USES THEREOF SENOMYX, INC. (US) 2009-02-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274632-A1 Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in composition and use thereof TAS2R50, TAS2R1, TAS2R30 TAS2R8 18/4885TAS2R14 28/4885
US-20200306156-A1 COOLING AND FLAVOR BOOSTING COMPOSITIONS TAS2R20, TAS2R10, TAS2R40 TAS2R8 8/4885TAS2R14 24/4885
US-11801209-B2 Cooling and flavor boosting compositions TAS2R20, TAS2R10, TAS2R40 TAS2R8 8/4885TAS2R14 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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