Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.48 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 13/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20571732 | 0.82 | ALDH1A3 (0.43) | SCDSCD5NOTUMHCRTR1HCRTR2 | |
| SCHEMBL1395242 | 0.81 | HDAC1 (0.49) | SCDSCD5HCRTR1HCRTR2 | |
| SCHEMBL3708569 | 0.81 | SCD5 (0.58) | SCDSCD5 | |
| SCHEMBL25393015 | 0.80 | HCRTR1 (0.51) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL25389498 | 0.80 | HCRTR1 (0.51) | HCRTR1HCRTR2CYP1A2 | |
| SCHEMBL1394565 | 0.77 | SCD (0.48) | SCDSCD5NOTUMCYP1A2 | |
| SCHEMBL3709763 | 0.76 | SCD5 (0.54) | SCDSCD5HCRTR2 | |
| SCHEMBL10112006 | 0.76 | BPTF (0.42) | SCDSCD5 | |
| SCHEMBL25389906 | 0.75 | NOTUM (0.51) | NOTUM | |
| SCHEMBL25390551 | 0.75 | NOTUM (0.51) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010186-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2012-01-12 | — | — | US | disclosed |
| WO-2010108268-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010186-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, FASN | SCD 1/4885SCD5 2/4885NOTUM 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.