Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 10/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16124187 | 0.81 | RBP4 (0.57) | RBP4AKR1C3TRPV1HCRTR1HCRTR2 | |
| SCHEMBL17502962 | 0.81 | RBP4 (0.52) | RBP4AKR1C3TTRTRPV1 | |
| SCHEMBL1395236 | 0.81 | RBP4 (0.52) | RBP4AKR1C3TTRTRPV1 | |
| SCHEMBL5239668 | 0.80 | AKR1C3 (0.68) | RBP4AKR1C3TTRTRPV1 | |
| SCHEMBL17515569 | 0.79 | RBP4 (0.58) | RBP4AKR1C3TRPV1HCRTR1HCRTR2 | |
| SCHEMBL17515547 | 0.79 | RBP4 (0.69) | RBP4TRPV1 | |
| SCHEMBL20533587 | 0.79 | RBP4 (0.50) | RBP4AKR1C3TTRTRPV1NOTUM | |
| SCHEMBL17515570 | 0.79 | RBP4 (0.65) | RBP4HCRTR1HCRTR2 | |
| SCHEMBL16124182 | 0.78 | RBP4 (0.56) | RBP4AKR1C3TRPV1HCRTR1HCRTR2 | |
| SCHEMBL17515571 | 0.77 | RBP4 (0.52) | RBP4AKR1C3TRPV1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010186-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2012-01-12 | — | — | US | disclosed |
| WO-2010108268-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010186-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, FASN | RBP4 602/4885AKR1C3 517/4885TTR 2860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.