Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 7/20 | 0.61 |
| ▸ | TERT | O14746 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.54 |
| ▸ | CASP3 | P42574 | 5/20 | 0.54 |
| ▸ | CDC37 | Q16543 | 5/20 | 0.54 |
| ▸ | PRDX1 | Q06830 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944035 | 0.89 | TERT (0.57) | NR4A1TERTPTPN1CASP1ABHD6 | |
| SCHEMBL20611 | 0.84 | NR4A1 (0.54) | NR4A1TERTPTPN1CASP1ABHD6 | |
| SCHEMBL13944031 | 0.81 | HSP90AA1 (0.57) | NR4A1TERTPTPN1CASP1ABHD6 | |
| SCHEMBL13944053 | 0.79 | NR4A1 (0.54) | NR4A1TERTPTPN1CASP1ABHD6 | |
| SCHEMBL13944047 | 0.76 | HSP90AB1 (0.54) | NR4A1TERTPTPN1CASP1ABHD6 | |
| SCHEMBL12395123 | 0.76 | NR4A1 (1.00) | NR4A1TERTPTPN1CASP1ABHD6 | |
| SCHEMBL18782343 | 0.75 | NR4A1 (0.74) | NR4A1TERTPTPN1CASP1ABHD6 | |
| SCHEMBL23054530 | 0.75 | HSP90AB1 (0.49) | NR4A1TERTPTPN1CASP1ABHD6 | |
| SCHEMBL18781890 | 0.73 | PRDX1 (0.80) | NR4A1TERTPTPN1CASP1ABHD6 | |
| SCHEMBL17124742 | 0.73 | NR4A1 (0.75) | NR4A1TERTPTPN1CASP1ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026163-A1 | COMPOSITIONS AND METHODS FOR INHIBITING GROWTH AND METASTASIS OF MELANOMA | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2009-02-26 | — | — | WO | disclosed |