Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944049 | 0.89 | MAPT (0.60) | MAPTGAALMNAPOLBKMT2A | |
| SCHEMBL22737771 | 0.81 | KMT2A (0.57) | MAPTGAALMNAPOLBKMT2A | |
| SCHEMBL22737390 | 0.79 | GBA1 (0.47) | MAPTGAALMNAPOLBKMT2A | |
| SCHEMBL13942939 | 0.78 | KMT2A (0.47) | MAPTGAALMNAPOLBKMT2A | |
| SCHEMBL8239323 | 0.77 | MAPT (0.51) | MAPTGAALMNAPOLBKMT2A | |
| SCHEMBL23345459 | 0.77 | KMT2A (0.72) | MAPTGAALMNAKMT2ASMN1; SMN2 | |
| SCHEMBL23345481 | 0.76 | KMT2A (0.70) | MAPTGAALMNAPOLBKMT2A | |
| SCHEMBL22737355 | 0.76 | MAPT (0.57) | MAPTGAALMNAPOLBKMT2A | |
| SCHEMBL13091227 | 0.76 | MAPT (0.61) | MAPTGAALMNAPOLBKMT2A | |
| SCHEMBL23345439 | 0.74 | KMT2A (0.67) | MAPTGAALMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023558-A1 | COMPOSITIONS AND METHODS FOR APOPTOSIS MODULATORS | VM DISCOVERY INC. (US) | 2009-02-19 | — | — | WO | disclosed |