Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13943387 | 0.78 | MAPT (0.60) | KMT2ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL22737390 | 0.76 | GBA1 (0.47) | KMT2ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL13944049 | 0.69 | MAPT (0.60) | KMT2ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL22737561 | 0.68 | GBA1 (0.49) | KMT2ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL8239323 | 0.68 | MAPT (0.51) | KMT2ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL26115021 | 0.67 | MAPT (0.80) | KMT2ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL31653615 | 0.67 | MAPT (0.80) | KMT2ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL26135108 | 0.67 | MAPT (0.80) | KMT2ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL22737355 | 0.67 | MAPT (0.57) | KMT2ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL22737771 | 0.67 | KMT2A (0.57) | KMT2ASMN1; SMN2GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023558-A1 | COMPOSITIONS AND METHODS FOR APOPTOSIS MODULATORS | VM DISCOVERY INC. (US) | 2009-02-19 | — | — | WO | disclosed |