Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238479 | 0.83 | MAPT (0.61) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL22737561 | 0.83 | GBA1 (0.49) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL22737771 | 0.80 | KMT2A (0.57) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL22737390 | 0.79 | GBA1 (0.47) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL14527861 | 0.79 | DDX3X (0.60) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL13943387 | 0.77 | MAPT (0.60) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL22737355 | 0.77 | MAPT (0.57) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL19016813 | 0.75 | MAPT (0.61) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL3059472 | 0.74 | MAPK1 (0.60) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL3059474 | 0.74 | MAPK1 (0.60) | MAPTKMT2AMEN1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007051333-A1 | TRIAZINE BETA-SECRETASE INHIBITORS | ONCALIS AG (CH) | 2007-05-10 | — | — | WO | disclosed |