Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | UGCG | Q16739 | 2/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922581 | 0.90 | GPBAR1 (0.34) | SCN9AGPBAR1FPR2TRPM8LTC4S | |
| SCHEMBL11922608 | 0.85 | LTC4S (0.36) | SCN9AGPBAR1FPR2TRPM8LTC4S | |
| SCHEMBL11922616 | 0.82 | EIF4EBP1 (0.35) | SCN9AGPBAR1FPR2TRPM8LTC4S | |
| SCHEMBL11922628 | 0.77 | SCN9A (0.36) | SCN9AFPR2P2RX3MRGPRX4P2RY1 | |
| SCHEMBL11922631 | 0.76 | GRM2 (0.30) | — | |
| SCHEMBL11922586 | 0.73 | FPR2 (0.41) | SCN9AFPR2P2RX3CCR2CYP3A4 | |
| SCHEMBL11922629 | 0.72 | P2RY1 (0.33) | SCN9AFPR2P2RX3CCR2P2RY1 | |
| SCHEMBL11991462 | 0.72 | SCN9A (0.38) | SCN9AFPR2LTC4SP2RX3PTGER4 | |
| SCHEMBL12763925 | 0.71 | SCN9A (0.42) | SCN9AGPBAR1FPR2P2RX3PTGER4 | |
| SCHEMBL11922615 | 0.70 | SCN9A (0.34) | SCN9ATRPM8LTC4SCYP3A4MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009018657-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-12 | — | — | WO | disclosed |