Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.80 |
| ▸ | BCDIN3D | Q7Z5W3 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 4/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13942957 | 0.88 | MEN1 (0.75) | MAPTTP53BCDIN3DMEN1KMT2A | |
| SCHEMBL13947571 | 0.86 | PDE2A (0.67) | MAPTTP53BCDIN3D | |
| SCHEMBL13944179 | 0.85 | MEN1 (0.74) | MAPTTP53BCDIN3DMEN1KMT2A | |
| SCHEMBL13942961 | 0.85 | SHMT2 (0.71) | MAPTTP53BCDIN3DMEN1KMT2A | |
| SCHEMBL13944346 | 0.83 | BCDIN3D (0.66) | MAPTTP53BCDIN3DMEN1KMT2A | |
| SCHEMBL13942965 | 0.82 | SHMT2 (0.77) | MAPTTP53BCDIN3DMEN1KMT2A | |
| SCHEMBL13942956 | 0.82 | MAPT (0.79) | MAPTTP53BCDIN3DMEN1KMT2A | |
| SCHEMBL13944173 | 0.81 | HTR2C (0.82) | MAPTTP53BCDIN3DMEN1KMT2A | |
| SCHEMBL13944356 | 0.80 | TP53 (0.74) | MAPTTP53BCDIN3DSHMT2HTR2C | |
| SCHEMBL22805935 | 0.79 | BCDIN3D (1.00) | BCDIN3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023978-A1 | PYRAZOLO [3,4 -D] PYRIMIDINE COMPOUNDS AND THEIR USE AS MODULATORS OF PROTEIN KINASE | ONCALIS AG (CH) | 2009-02-26 | — | — | WO | disclosed |