Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL28124054 | 0.95 | TDP1 (0.67) | TDP1LMNAALOX15HSD17B10ALDH1A1 | |
| Acrylic Acid SCHEMBL551868 | 0.95 | TDP1 (0.67) | TDP1LMNAALOX15HSD17B10ALDH1A1 | |
| Acrylic Acid SCHEMBL27625307 | 0.92 | TDP1 (0.63) | TDP1LMNAALOX15HSD17B10ALDH1A1 | |
| Methacrylic Acid SCHEMBL28150989 | 0.92 | LMNA (0.53) | TDP1LMNAALOX15HSD17B10ALDH1A1 | |
| Methacrylic Acid SCHEMBL1890911 | 0.90 | ALDH1A1 (0.55) | TDP1LMNAALOX15HSD17B10ALDH1A1 | |
| Methacrylic Acid SCHEMBL28878259 | 0.90 | TDP1 (0.60) | TDP1LMNAALOX15HSD17B10ALDH1A1 | |
| Methacrylic Acid SCHEMBL8024489 | 0.90 | LMNA (0.56) | TDP1LMNAALOX15HSD17B10ALDH1A1 | |
| Methacrylic Acid SCHEMBL23071293 | 0.89 | LMNA (0.62) | TDP1LMNAALOX15HSD17B10ALDH1A1 | |
| Methacrylic Acid SCHEMBL5964487 | 0.89 | LMNA (0.62) | TDP1LMNAALOX15HSD17B10ALDH1A1 | |
| Methacrylic Acid SCHEMBL137716 | 0.89 | LMNA (0.62) | TDP1LMNAALOX15HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009621-A1 | NOVEL ANTIBODY AND ANTIBODY FRAGMENT INTRODUCED NEW MODIFICATION SITES | KYOWA HAKKO KIRIN CO., LTD (JP) | 2012-01-12 | — | — | US | disclosed |