Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13943704 | 0.88 | HTR2C (0.60) | HTR2CPIK3CA | |
| SCHEMBL13943327 | 0.81 | TP53 (0.60) | HTR2CPIK3CAKMT2A | |
| SCHEMBL13946809 | 0.80 | HTR2C (0.68) | HTR2CPIK3CA | |
| SCHEMBL13942987 | 0.80 | PDE2A (0.66) | HTR2CKMT2A | |
| SCHEMBL13943298 | 0.79 | HTR2C (0.61) | HTR2C | |
| SCHEMBL13944194 | 0.79 | HTR2C (0.80) | HTR2CPIK3CA | |
| SCHEMBL13947359 | 0.79 | HTR2C (0.62) | HTR2CPIK3CA | |
| SCHEMBL13943676 | 0.78 | KDM4E (0.62) | HTR2CPIK3CAKMT2A | |
| SCHEMBL13942982 | 0.78 | HTR2C (0.74) | HTR2CPIK3CA | |
| SCHEMBL13942993 | 0.77 | HTR2C (0.74) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025678-A1 | Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase | Oncalis AG (CH) | 2009-02-18 | — | — | EP | disclosed |