Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 3/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 10/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947015 | 0.85 | PTK2 (0.38) | PTK2RIPK1KDM4EMEN1ALDH1A1 | |
| SCHEMBL13044755 | 0.83 | CFTR (0.46) | PTK2RIPK1KDM4EALDH1A1CFTR | |
| SCHEMBL11922595 | 0.82 | PTK2 (0.34) | PTK2RIPK1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11991544 | 0.81 | PTK2 (0.37) | PTK2LRRK2CFTR | |
| SCHEMBL13947012 | 0.81 | PTK2 (0.32) | PTK2HCRTR1HCRTR2 | |
| SCHEMBL11991542 | 0.80 | PRKCQ (0.38) | PTK2LRRK2CFTRHCRTR1HCRTR2 | |
| SCHEMBL13044752 | 0.79 | PTK2 (0.33) | PTK2RIPK1 | |
| SCHEMBL11922636 | 0.79 | PTK2 (0.39) | PTK2LRRK2 | |
| SCHEMBL13044788 | 0.79 | PTK2 (0.32) | PTK2RIPK1 | |
| SCHEMBL11991450 | 0.79 | PTK2 (0.36) | PTK2RIPK1LRRK2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2B | PTK2 4679/4885RIPK1 3090/4885KDM4E 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.