Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898932 | 0.94 | MAOB (0.37) | MAOBL3MBTL1KMT2APIK3CDABL1 | |
| SCHEMBL23034556 | 0.84 | ESR1 (0.41) | MAOBKMT2AESR1ESR2CYP2A6 | |
| SCHEMBL6923032 | 0.81 | MAOB (0.43) | MAOBL3MBTL1KMT2AESR1MEN1 | |
| SCHEMBL10441823 | 0.80 | CYP2A6 (0.57) | MAOBCYP2A6SLC6A4ALDH1A1MAOA | |
| SCHEMBL9367875 | 0.78 | TAAR1 (0.55) | CYP2A6SLC6A4MAOA | |
| SCHEMBL10898565 | 0.77 | BDKRB2 (0.45) | MAOBPIK3CDABL1EGFRHCK | |
| SCHEMBL15161169 | 0.76 | TP53 (0.42) | L3MBTL1ESR1ESR2CYP2A6TRPA1 | |
| SCHEMBL20902563 | 0.76 | MEN1 (0.42) | MAOBKMT2AESR1PIK3CDABL1 | |
| SCHEMBL14370178 | 0.76 | ALDH1A1 (0.40) | L3MBTL1ESR1ESR2PKMTDP1 | |
| SCHEMBL21462931 | 0.76 | SLC6A4 (0.38) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495020-B2 | 2-aryloxy-2-arylalkanoic acids for diabetes and lipid disorders | MERCK & CO., INC. (US) | 2009-02-24 | — | — | US | disclosed |