Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 2/20 | 0.78 |
| ▸ | HTR2C | P28335 | 4/20 | 0.68 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.64 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.59 |
| ▸ | GALR2 | O43603 | 1/20 | 0.56 |
| ▸ | GALR1 | P47211 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13944738 | 0.88 | SHMT2 (1.00) | SHMT2HTR2CBCDIN3D | |
| SCHEMBL13944735 | 0.87 | SHMT2 (0.98) | SHMT2HTR2CBCDIN3DGALR2GALR1 | |
| SCHEMBL13943679 | 0.87 | HTR2C (0.69) | SHMT2HTR2CPIK3CABCDIN3D | |
| SCHEMBL13947206 | 0.86 | SHMT2 (0.59) | SHMT2HTR2CPIK3CABCDIN3D | |
| SCHEMBL13943713 | 0.86 | KMT2A (0.74) | SHMT2HTR2CBCDIN3D | |
| SCHEMBL13943729 | 0.82 | HTR2C (0.98) | SHMT2HTR2CBCDIN3D | |
| SCHEMBL13944737 | 0.82 | BCDIN3D (0.71) | SHMT2HTR2CPIK3CABCDIN3D | |
| SCHEMBL13943259 | 0.82 | HTR2C (0.74) | SHMT2HTR2CBCDIN3D | |
| SCHEMBL13943727 | 0.81 | HTR2C (1.00) | SHMT2HTR2CBCDIN3D | |
| SCHEMBL13946808 | 0.81 | PIK3CA (0.66) | SHMT2HTR2CPIK3CABCDIN3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2025678-A1 | Pyrazolo[3,4-d]pyrimidine compounds and their use as modulators of protein kinase | Oncalis AG (CH) | 2009-02-18 | — | — | EP | disclosed |