SCHEMBL1395101

SCHEMBL1395101

c1ccc2c(c1)-c1ccccc1C2(C1CCCCC1)C1CCCCC1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.41
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1394180 0.98 KMT2A (0.40) PDK2KMT2A
SCHEMBL23071373 0.85 PDK2 (0.33) PDK2KMT2A
SCHEMBL2968002 0.85 PDK2 (0.33) PDK2KMT2A
SCHEMBL13713752 0.81 PDK2 (0.42) PDK2KMT2A
SCHEMBL30949491 0.81 KMT2A (0.42) PDK2KMT2A
SCHEMBL7312265 0.79 PDK2 (0.45) PDK2KMT2A
SCHEMBL2412905 0.79
SCHEMBL2409360 0.79 PDK2 (0.32) PDK2
SCHEMBL30611509 0.79 PDK2 (0.37) PDK2KMT2A
SCHEMBL4451439 0.77 KMT2A (0.38) PDK2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120007059-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND COMPOUND IDEMITSU KOSAN CO., LTD. (JP) 2012-01-12 US disclosed
CN-102265423-A Organic electroluminescent element and compound 2011-11-30 CN disclosed
EP-2372804-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND COMPOUND Idemitsu Kosan Co., Ltd. (JP) 2011-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120007059-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND COMPOUND LEF1, EBPL, L1CAM PDK2 1397/4885KMT2A 1152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.