Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791505 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL265072 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL10556768 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL301766 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL3382944 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL265657 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL9885352 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL11930055 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL6917395 | 0.97 | EPHX1 (0.60) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL12529955 | 0.97 | EPHX1 (0.60) | EPHX1CA1CA2CA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054472-A1 | Pyrazolopyrimidine Derivatives or Pharmaceutically Acceptable Salts Thereof | TEIJIN PHARMA LIMITED (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054472-A1 | Pyrazolopyrimidine Derivatives or Pharmaceutically Acceptable Salts Thereof | MAPKAPK2, MAPKAPK5, MAPKAPK3 | EPHX1 3501/4885CA1 2793/4885CA2 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.