Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PEPD | P12955 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13952183 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL265072 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL10556768 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL301766 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL3382944 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL265657 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL9885352 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL11930055 | 1.00 | EPHX1 (0.62) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL6917395 | 0.97 | EPHX1 (0.60) | EPHX1CA1CA2CA4MEN1 | |
| SCHEMBL12529955 | 0.97 | EPHX1 (0.60) | EPHX1CA1CA2CA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772450-B2 | Beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-03-22 | — | — | US | disclosed |
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-03-22 | — | — | US | disclosed |
| US-20120021530-A1 | HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2012-01-26 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7884074-B2 | Compounds and methods for prevention and/or treatment of inflammation using the same | Ikaria Development Subsidiary Two, LLC (US) | 2011-02-08 | — | — | US | disclosed |
| EP-1406872-B1 | DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES | MERCK & CO INC (US) | 2007-12-19 | — | — | EP | disclosed |
| US-20070049593-A1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-0814073-B1 | Epimerization of 2- or 4-substituted cyclohexanecarboxylic acids | KATAYAMA SEISAKUSHO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5831118-A | HEATING WITH POTASSIUM HYDROXIDE; ONE STEP | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0814073-A1 | Epimerization of 2- or 4-substituted cyclohexanecarboxylic acids | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1997-12-29 | — | — | EP | disclosed |
| EP-0340971-B1 | Attractants for the Mediterranean fruit fly | US COMMERCE (US) | 1994-01-19 | — | — | EP | disclosed |
| EP-0340971-A3 | ATTRACTANTS FOR THE MEDITERRANEAN FRUIT FLY | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1991-09-11 | — | — | EP | disclosed |
| EP-0340971-A2 | Attractants for the Mediterranean fruit fly | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1989-11-08 | — | — | EP | disclosed |
| EP-0340971-A2 | Attractants for the Mediterranean fruit fly | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1989-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070049593-A1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | POLI, TERT, ZC3HAV1 | EPHX1 3653/4885CA1 3203/4885CA2 2701/4885 |
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | POLI, TERT, ZC3HAV1 | EPHX1 3653/4885CA1 3203/4885CA2 2701/4885 |
| US-20120021530-A1 | HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS | DNPEP, PRKCSH, YWHAZ | EPHX1 3782/4885CA1 1198/4885CA2 3048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.