Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13952599 | 0.88 | TDP1 (0.45) | TDP1TP53SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL13952597 | 0.71 | NFE2L2 (0.45) | TDP1KDM4EALDH1A1ATM | |
| SCHEMBL9592335 | 0.69 | TDP1 (0.48) | TDP1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL2065074 | 0.68 | CA1 (0.42) | KDM4E | |
| SCHEMBL14261346 | 0.66 | TSHR (0.48) | TDP1TP53SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5776485 | 0.65 | — | — | |
| SCHEMBL35226 | 0.65 | — | — | |
| SCHEMBL7024646 | 0.65 | — | — | |
| SCHEMBL4035490 | 0.65 | NFE2L2 (0.43) | TDP1NPC1RAB9ASMN1; SMN2KDM4E | |
| 2,4-Dichlorofluorobenzene SCHEMBL530773 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021999-A1 | CROSS-LINKABLE POLY(ARYL ETHER KETONE)S AND ARTICLES MADE THEREFROM | SOLVAY SPECIALITIES INDIA PRIVATE LIMITED (IN) | 2009-02-19 | — | — | WO | disclosed |