Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2065074 | 0.74 | CA1 (0.42) | NFE2L2CES2CES1CA9KDM4E | |
| SCHEMBL13107429 | 0.71 | CES2 (0.43) | NFE2L2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL14566097 | 0.71 | ALDH1A1 (0.42) | NFE2L2ALDH1A1CES2CES1CA3 | |
| SCHEMBL13952598 | 0.71 | TDP1 (0.39) | ALDH1A1ATMTDP1KDM4E | |
| SCHEMBL3298105 | 0.65 | NFE2L2 (0.58) | NFE2L2ALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1241955 | 0.63 | CES2 (0.44) | ALDH1A1CES2CES1CA3CA6 | |
| SCHEMBL180042 | 0.63 | — | — | |
| SCHEMBL29352228 | 0.63 | — | — | |
| SCHEMBL21030098 | 0.62 | NFE2L2 (1.00) | NFE2L2PTGS1PTGS2 | |
| SCHEMBL4905475 | 0.62 | NFE2L2 (0.54) | NFE2L2ALDH1A1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021999-A1 | CROSS-LINKABLE POLY(ARYL ETHER KETONE)S AND ARTICLES MADE THEREFROM | SOLVAY SPECIALITIES INDIA PRIVATE LIMITED (IN) | 2009-02-19 | — | — | WO | disclosed |