Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30073229 | 0.77 | AHR (0.78) | AHRTP53CYP1B1CYP1A2CNR1 | |
| SCHEMBL1520954 | 0.77 | AHR (0.78) | AHRTP53CYP1B1CYP1A2CNR1 | |
| SCHEMBL2063634 | 0.76 | LMNA (0.57) | TP53CYP1A2MAPK1LMNAMEN1 | |
| SCHEMBL13952601 | 0.75 | HSD17B10 (0.58) | TP53ALOX5MAPTMAPK1LMNA | |
| SCHEMBL3952742 | 0.68 | CYP1A2 (0.73) | AHRTP53CYP1A2ALOX5MAPK1 | |
| SCHEMBL11165087 | 0.68 | CYP1A2 (0.73) | AHRTP53CYP1A2ALOX5MAPK1 | |
| SCHEMBL28215 | 0.68 | CYP1A2 (0.73) | AHRTP53CYP1A2ALOX5MAPK1 | |
| SCHEMBL20083331 | 0.66 | CYP1A2 (0.48) | AHRCYP1A2BACE1ALOX5LMNA | |
| SCHEMBL8042030 | 0.66 | HSD17B10 (0.46) | AHRTP53CYP1B1EPHX1EPHX2 | |
| SCHEMBL9160072 | 0.66 | AHR (0.68) | AHRCYP1A2BACE1ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009021999-A1 | CROSS-LINKABLE POLY(ARYL ETHER KETONE)S AND ARTICLES MADE THEREFROM | SOLVAY SPECIALITIES INDIA PRIVATE LIMITED (IN) | 2009-02-19 | — | — | WO | disclosed |