Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13952883 | 0.83 | CNR1 (0.48) | OPRM1CNR1CNR2 | |
| SCHEMBL4700951 | 0.79 | OPRM1 (0.48) | OPRM1CNR1CNR2KDR | |
| SCHEMBL279758 | 0.79 | OPRM1 (0.48) | OPRM1CNR1CNR2KDR | |
| SCHEMBL5095397 | 0.79 | OPRM1 (0.48) | OPRM1CNR1CNR2KDR | |
| SCHEMBL11484472 | 0.79 | CNR2 (0.66) | CNR1CNR2KDR | |
| SCHEMBL13589104 | 0.78 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL22411749 | 0.77 | CNR2 (0.59) | OPRM1CNR1CNR2 | |
| SCHEMBL279392 | 0.76 | KDR (0.57) | OPRM1CNR1CNR2KDR | |
| SCHEMBL5097376 | 0.76 | KDR (0.57) | OPRM1CNR1CNR2KDR | |
| SCHEMBL4700013 | 0.76 | KDR (0.57) | OPRM1CNR1CNR2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054376-A1 | BENZOFURAN DERIVATIVES WITH THERAPEUTIC ACTIVITIES | PHARMOS CORPORATION | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054376-A1 | BENZOFURAN DERIVATIVES WITH THERAPEUTIC ACTIVITIES | CNR2, CNR1, TRPV1 | OPRM1 83/4885CNR1 2/4885CNR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.