Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279758 | 1.00 | OPRM1 (0.48) | OPRM1CNR2CNR1KDR | |
| SCHEMBL4700951 | 1.00 | OPRM1 (0.48) | OPRM1CNR2CNR1KDR | |
| SCHEMBL13952884 | 0.79 | OPRM1 (0.49) | OPRM1CNR2CNR1KDR | |
| SCHEMBL4703155 | 0.78 | CNR2 (0.35) | OPRM1CNR2CNR1 | |
| SCHEMBL275356 | 0.78 | CNR2 (0.35) | OPRM1CNR2CNR1 | |
| SCHEMBL279652 | 0.78 | CNR2 (0.35) | OPRM1CNR2CNR1 | |
| SCHEMBL5097829 | 0.78 | CNR2 (0.35) | OPRM1CNR2CNR1 | |
| SCHEMBL279756 | 0.78 | CNR2 (0.35) | OPRM1CNR2CNR1 | |
| SCHEMBL13952883 | 0.77 | CNR1 (0.48) | OPRM1CNR2CNR1 | |
| SCHEMBL16298825 | 0.76 | STS (0.39) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312224-A1 | Oxaphenanthrene Derivatives | MERCK PATENT GMBH (DE) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312224-A1 | Oxaphenanthrene Derivatives | CYP3A43, CYP1A1, CYP1A2 | OPRM1 281/4885CNR2 1588/4885CNR1 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.