Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | BRS3 | P32247 | 6/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.34 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14145262 | 0.83 | BRS3 (0.43) | GPR84BRS3S1PR4S1PR1S1PR5 | |
| SCHEMBL14145145 | 0.81 | SPTLC1 (0.41) | GPR84BRS3S1PR4S1PR1S1PR5 | |
| SCHEMBL13953372 | 0.77 | S1PR1 (0.41) | S1PR4S1PR1S1PR5S1PR3 | |
| SCHEMBL13953201 | 0.75 | S1PR1 (0.48) | S1PR4S1PR1S1PR5S1PR3 | |
| SCHEMBL2622476 | 0.73 | HRH4 (0.47) | BRS3 | |
| SCHEMBL13932736 | 0.68 | S1PR1 (0.66) | S1PR4S1PR1S1PR5S1PR3 | |
| SCHEMBL13953091 | 0.68 | S1PR4 (0.42) | GPR84S1PR4S1PR1S1PR5 | |
| SCHEMBL2632242 | 0.65 | S1PR1 (0.67) | S1PR4S1PR1S1PR5S1PR3 | |
| SCHEMBL13932767 | 0.65 | S1PR1 (0.67) | S1PR4S1PR1S1PR5S1PR3 | |
| SCHEMBL3108002 | 0.65 | ARG2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009023059-A2 | TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-02-19 | — | — | WO | disclosed |