Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622466 | 0.93 | PGR (0.32) | PGRMAPTTP53NPSR1ALDH1A1 | |
| (Rs)-Indanofan SCHEMBL65575 | 0.90 | SLC6A3 (0.40) | PGRMAPTTP53NPSR1ALDH1A1 | |
| (Rs)-Indanofan SCHEMBL29490898 | 0.90 | SLC6A3 (0.40) | PGRMAPTTP53NPSR1ALDH1A1 | |
| (R)-Indanofan SCHEMBL30750972 | 0.90 | SLC6A3 (0.40) | PGRMAPTTP53NPSR1ALDH1A1 | |
| (Rs)-Indanofan SCHEMBL28281074 | 0.89 | SLC6A3 (0.39) | PGRMAPTTP53NPSR1ALDH1A1 | |
| SCHEMBL7057276 | 0.88 | UTS2R (0.42) | PGRMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL2622454 | 0.85 | MAPT (0.39) | MAPTTP53NPSR1ALDH1A1ALOX12 | |
| SCHEMBL13953152 | 0.81 | SLC6A3 (0.37) | PGRSLC6A4CHRNA1CHRNB1CHRNB2 | |
| SCHEMBL2622458 | 0.81 | NPSR1 (0.43) | MAPTNPSR1ALDH1A1LMNAUTS2R | |
| SCHEMBL7057272 | 0.80 | GRIN1 (0.40) | PGRMAPTNPSR1ALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9757407-B2 | Treatment of viral infections by modulation of host cell metabolic pathways | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-09-12 | — | — | US | disclosed |
| EP-2581081-A2 | Treatment of viral infections by modulation of host cell metabolic pathways | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-04-17 | — | — | EP | disclosed |
| EP-2572712-A2 | Treatment of viral infections by modulation of host cell metabolic pathways | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2009023059-A2 | TREATMENT OF VIRAL INFECTIONS BY MODULATION OF HOST CELL METABOLIC PATHWAYS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-02-19 | — | — | WO | disclosed |