Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.32 |
| ▸ | PYGB | P11216 | 1/20 | 0.32 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.31 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22054343 | 0.79 | MAPK1 (0.43) | LGALS8LGALS3LGALS4 | |
| SCHEMBL19940051 | 0.79 | — | — | |
| SCHEMBL17636459 | 0.78 | AMY1A (0.43) | AMY1ASTAT3PYGBLGALS8 | |
| SCHEMBL19276587 | 0.78 | AMY1A (0.43) | AMY1ASTAT3PYGBLGALS8 | |
| SCHEMBL16588594 | 0.78 | AMY1A (0.43) | AMY1ASTAT3PYGBLGALS8 | |
| SCHEMBL19271988 | 0.78 | AMY1A (0.43) | AMY1ASTAT3PYGBLGALS8 | |
| SCHEMBL19276586 | 0.78 | AMY1A (0.43) | AMY1ASTAT3PYGBLGALS8 | |
| SCHEMBL19018542 | 0.78 | AMY1A (0.43) | AMY1ASTAT3PYGBLGALS8 | |
| SCHEMBL17753791 | 0.78 | AMY1A (0.43) | AMY1ASTAT3PYGBLGALS8 | |
| SCHEMBL18104476 | 0.78 | AMY1A (0.43) | AMY1ASTAT3PYGBLGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381361-B1 | COMBINATION THERAPY COMPRISING GLUCOSE REABSORPTION INHIBITORS AND PPAR MODULATORS | ORTHO MCNEIL JANSSEN PHARM (US) | 2009-02-25 | — | — | EP | disclosed |