Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | AMY2A | P04746 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | PYGB | P11216 | 1/20 | 0.35 |
| ▸ | FGF1 | P05230 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15958769 | 1.00 | AMY1A (0.43) | AMY1AAMY2ASLC5A2LGALS8STAT3 | |
| SCHEMBL19276586 | 1.00 | AMY1A (0.43) | AMY1AAMY2ASLC5A2LGALS8STAT3 | |
| SCHEMBL16588594 | 1.00 | AMY1A (0.43) | AMY1AAMY2ASLC5A2LGALS8STAT3 | |
| SCHEMBL19271988 | 1.00 | AMY1A (0.43) | AMY1AAMY2ASLC5A2LGALS8STAT3 | |
| SCHEMBL17636459 | 1.00 | AMY1A (0.43) | AMY1AAMY2ASLC5A2LGALS8STAT3 | |
| SCHEMBL19276587 | 1.00 | AMY1A (0.43) | AMY1AAMY2ASLC5A2LGALS8STAT3 | |
| SCHEMBL17753791 | 1.00 | AMY1A (0.43) | AMY1AAMY2ASLC5A2LGALS8STAT3 | |
| SCHEMBL17636456 | 1.00 | AMY1A (0.43) | AMY1AAMY2ASLC5A2LGALS8STAT3 | |
| SCHEMBL19018542 | 1.00 | AMY1A (0.43) | AMY1AAMY2ASLC5A2LGALS8STAT3 | |
| SCHEMBL13647094 | 1.00 | AMY1A (0.43) | AMY1AAMY2ASLC5A2LGALS8STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170239341-A1 | VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-08-24 | — | — | US | disclosed |
| US-20160279224-A1 | PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170239341-A1 | VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 8 | LGALS8, SIGLEC7, FUT5 | AMY1A 1174/4885AMY2A 1783/4885SLC5A2 899/4885 |
| US-20160279224-A1 | PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 | STT3A, DDOST, LGALS3BP | AMY1A 2691/4885AMY2A 2750/4885SLC5A2 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.