Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.55 |
| ▸ | LOX | P28300 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30238692 | 1.00 | ALOX5 (0.55) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL28657389 | 1.00 | ALOX5 (0.55) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL79534 | 0.83 | ALOX5 (0.54) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL1444769 | 0.80 | ALOX5 (0.55) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL2161082 | 0.80 | ALOX5 (0.51) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL16399862 | 0.80 | ALOX5 (0.55) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL1706446 | 0.80 | ALOX5 (0.51) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL4361286 | 0.80 | ALOX5 (0.51) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9602556 | 0.79 | ALOX5 (0.51) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9565151 | 0.79 | ALOX5 (0.48) | ALOX5CYP1A2PTGESLMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096715-A | Beneficial benzothiophene compositions for mental disorders or enhancement | 泰科根公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-3917914-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2021-12-08 | — | — | EP | disclosed |
| CN-113646300-A | Diamino-substituted pyridines and pyrimidines as herbicides | FMC公司 | 2021-11-12 | — | — | CN | disclosed |
| EP-3760620-A1 | RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USAGE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| WO-2020160202-A1 | DIAMINO-SUBSTITUTED PYRIDINES AND PYRIMIDINES AS HERBICIDES | FMC CORPORATION (US) | 2020-08-06 | — | — | WO | disclosed |
| WO-2018048930-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
| WO-2017079867-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-05-18 | — | — | WO | disclosed |
| US-8883824-B2 | 3-(4-aminophenyl)-2-furancarboxylic acid derivative and pharmaceutically acceptable salt thereof | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-1575951-B1 | HETEROCYCLIC COMPOUNDS, METHODS OF MAKING THEM AND THEIR USE IN THERAPY | DEBIOPHARM INT SA (CH) | 2014-06-25 | — | — | EP | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| WO-2004052890-A1 | HETEROCYCLIC COMPOUNDS, METHODS OF MAKING THEM AND THEIR USE IN THERAPY | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2004-06-24 | — | — | WO | disclosed |
| EP-0589784-B1 | 2-Ethyl-benzo(b)thiophene derivative, process of its preparation and its use as intermediate for synthesis | SANOFI SA (FR) | 1997-12-17 | — | — | EP | disclosed |
| US-5420300-A | Chemical intermediate for leukotriene inhibitor | ELF SANOFI (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0589784-A1 | 2-Ethyl-benzo(b)thiophene derivative, process of its preparation and its use as intermediate for synthesis | SANOFI (FR) | 1994-03-30 | — | — | EP | disclosed |
| EP-0283522-B1 | TRIAZINE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING SAME AS EFFECTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4932998-A | LOW PHYTOTOXICITY FOR PADDY RICE PLANTS | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0216259-B1 | TRIAZINE DERIVATIVES, A PROCESS FOR PREPARATION OF THE DERIVATIVES, AND HERBICIDES CONTAINING THE DERIVATIVES AS THE EFFECTIVE COMPONENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-02-28 | — | — | EP | disclosed |
| EP-0283522-A1 | TRIAZINE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING SAME AS EFFECTIVE INGREDIENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-09-28 | — | — | EP | disclosed |
| US-4740230-A | Triazine derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-04-26 | — | — | US | disclosed |
| EP-0216259-A1 | Triazine derivatives, a process for preparation of the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-04-01 | — | — | EP | disclosed |