Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.55 |
| ▸ | LOX | P28300 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001061 | 0.85 | UGT2B7 (0.44) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL6001069 | 0.85 | UGT2B7 (0.44) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL9824749 | 0.85 | ALOX5 (0.53) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL2963101 | 0.83 | ALOX5 (0.50) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL79534 | 0.83 | ALOX5 (0.54) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL23782345 | 0.80 | ALOX5 (0.49) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL4361286 | 0.80 | ALOX5 (0.51) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL19880957 | 0.80 | MGLL (0.50) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL16399862 | 0.80 | ALOX5 (0.55) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL1706446 | 0.80 | ALOX5 (0.51) | ALOX5CYP1A2PTGESLMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670176-B2 | Process for the preparation of zileuton | STRIDES SHASUN LIMITED (IN) | 2017-06-06 | — | — | US | claimed |
| US-20160376251-A1 | Process for the Preparation of Zileuton | STRIDES SHASUN LIMITED (IN) | 2016-12-29 | — | — | US | claimed |
| US-8933250-B2 | Process for the preparation of N-(1-benzo[b]thien-2-ylethyl)-N-hydroxyurea | FARMAK, A.S. (CZ) | 2015-01-13 | — | — | US | claimed |
| US-20110184189-A1 | PROCESS FOR THE PREPARATION OF N-(1-BENZO[B]THIEN-2-YLETHYL)-N-HYDROXYUREA | FARMAK, A.S. (CZ) | 2011-07-28 | — | — | US | claimed |
| WO-2011036680-A2 | IMPROVED PROCESS FOR THE PREPARATION OF (±)-1-(1-BENZO[B]THIEN-2-YLETHYL)-1-HYDROXYUREA | MSN LABORATORIES LIMITED (IN) | 2011-03-31 | — | — | WO | claimed |
| WO-2010012246-A1 | A PROCESS FOR THE PREPARATION OF N-(1-BENZO[B]THIEN-2-YLETHYL)-N-HYDROXYUREA | FARMAK, A.S. (CZ) | 2010-02-04 | — | — | WO | claimed |
| US-12493241-B2 | Photoacid generators, photoresist compositions, and pattern formation methods | DUPONT ELECTRONIC MAT INTERNATIONAL LLC (US) | 2025-12-09 | — | — | US | disclosed |
| US-20250116927-A1 | PHOTOACID GENERATORS, PHOTORESIST COMPOSITIONS, AND PATTERN FORMATION METHODS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2025-04-10 | — | — | US | disclosed |
| US-20220214614-A1 | PHOTOACID GENERATORS, PHOTORESIST COMPOSITIONS, AND PATTERN FORMATION METHODS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2022-07-07 | — | — | US | disclosed |
| WO-2020035729-A1 | TOPICAL OLEAGINOUS COMPOSITIONS | DR. REDDY'S LABORATORIES LTD. (IN) | 2020-02-20 | — | — | WO | disclosed |
| US-9670176-B2 | Process for the preparation of zileuton | STRIDES SHASUN LIMITED (IN) | 2017-06-06 | — | — | US | disclosed |
| US-9670176-B2 | Process for the preparation of zileuton | STRIDES SHASUN LIMITED (IN) | 2017-06-06 | — | — | US | disclosed |
| US-9670176-B2 | Process for the preparation of zileuton | STRIDES SHASUN LIMITED (IN) | 2017-06-06 | — | — | US | disclosed |
| US-20090286996-A1 | PROCESS FOR THE PREPARATION OF ZILEUTON | DIPHARMA FRANCIS S.R.I. (IT) | 2009-11-19 | — | — | US | disclosed |
| US-6080874-A | Synthesis and isolation of N-(aryl or heteroaryl)-alkyl-N-hydroxyurea | ABBOTT LABORATORIES (US) | 2000-06-27 | — | — | US | disclosed |
| EP-0589784-B1 | 2-Ethyl-benzo(b)thiophene derivative, process of its preparation and its use as intermediate for synthesis | SANOFI SA (FR) | 1997-12-17 | — | — | EP | disclosed |
| US-5420300-A | Chemical intermediate for leukotriene inhibitor | ELF SANOFI (FR) | 1995-05-30 | — | — | US | disclosed |
| US-5405864-A | Chemotherapeutic maleimides | SYNTEX (U.S.A.) INC. (US) | 1995-04-11 | — | — | US | disclosed |
| EP-0589784-A1 | 2-Ethyl-benzo(b)thiophene derivative, process of its preparation and its use as intermediate for synthesis | SANOFI (FR) | 1994-03-30 | — | — | EP | disclosed |
| US-5183818-A | Also for inhibiting leukotriene biosynthesis | ABBOTT LABORATORIES (US) | 1993-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12493241-B2 | Photoacid generators, photoresist compositions, and pattern formation methods | ARF1, ARL1, GNA11 | ALOX5 1970/4885CYP1A2 528/4885PTGES 2740/4885 |
| US-20160376251-A1 | Process for the Preparation of Zileuton | CYP2B6, UGT1A6, CYP2A6 | ALOX5 124/4885CYP1A2 35/4885PTGES 1385/4885 |
| US-20110184189-A1 | PROCESS FOR THE PREPARATION OF N-(1-BENZO[B]THIEN-2-YLETHYL)-N-HYDROXYUREA | NUDT1, SLC29A1, SLC9A1 | ALOX5 2404/4885CYP1A2 614/4885PTGES 1990/4885 |
| US-20090286996-A1 | PROCESS FOR THE PREPARATION OF ZILEUTON | MPO, ZYX, F7 | ALOX5 420/4885CYP1A2 189/4885PTGES 2885/4885 |
| US-20250116927-A1 | PHOTOACID GENERATORS, PHOTORESIST COMPOSITIONS, AND PATTERN FORMATION METHODS | ARF1, ARL1, GNA11 | ALOX5 1970/4885CYP1A2 528/4885PTGES 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.