Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 9/20 | 0.43 |
| ▸ | ADH1C | P00326 | 6/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397010 | 0.83 | ADH1A (0.41) | ADH1AADH1CADH1BPIK3CDHRH4 | |
| SCHEMBL14098310 | 0.77 | PIK3CD (0.42) | ADH1AADH1CADH1BPIK3CDHRH4 | |
| SCHEMBL29957190 | 0.74 | ADH1A (0.54) | ADH1AADH1CADH1BHRH4HRH3 | |
| SCHEMBL3938593 | 0.74 | ADH1A (0.54) | ADH1AADH1CADH1BHRH4HRH3 | |
| SCHEMBL10451583 | 0.74 | PIK3CD (0.63) | ADH1AADH1CADH1BPIK3CDHRH4 | |
| SCHEMBL17921648 | 0.73 | KMT2A (0.42) | ADH1AADH1CADH1BPIK3CDHRH4 | |
| SCHEMBL17828082 | 0.73 | KMT2A (0.42) | ADH1AADH1CADH1BPIK3CDHRH4 | |
| SCHEMBL17923280 | 0.72 | ADH1C (0.37) | ADH1AADH1CADH1BPIK3CDHRH4 | |
| SCHEMBL29957698 | 0.72 | ADH1A (0.50) | ADH1AADH1CADH1BHRH4HRH3 | |
| SCHEMBL13683785 | 0.72 | PIK3CD (0.65) | ADH1AADH1CADH1BPIK3CDHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807072-B1 | CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | LILLY CO ELI (US) | 2009-01-07 | — | — | EP | disclosed |