Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13956323 | 0.93 | MAOB (0.47) | MAOBMAOAMAPTALDH1A1GAA | |
| SCHEMBL13956334 | 0.85 | HPGD (0.47) | MAOBMAPTALDH1A1GAAHPGD | |
| SCHEMBL13971161 | 0.85 | ALDH1A1 (0.44) | MAOBMAPTALDH1A1GAAHPGD | |
| SCHEMBL4699493 | 0.83 | MAOB (0.65) | MAOBMAOAPTPN1MAPTALDH1A1 | |
| SCHEMBL4699500 | 0.83 | MAOB (0.65) | MAOBMAOAPTPN1MAPTALDH1A1 | |
| SCHEMBL13971253 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1GAAHPGDKDM4E | |
| SCHEMBL13785972 | 0.75 | MAOB (0.62) | MAOBMAOAPTPN1MAPTALDH1A1 | |
| SCHEMBL7269573 | 0.74 | MAOB (0.60) | MAOBMAOAMAPTALDH1A1GAA | |
| SCHEMBL7269575 | 0.74 | MAOB (0.60) | MAOBMAOAMAPTALDH1A1GAA | |
| SCHEMBL4696465 | 0.74 | MAOB (0.55) | MAOBMAOAPTPN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005321-A1 | Phenylazetidinone Derivatives | MICROBIA, INC. (US) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005321-A1 | Phenylazetidinone Derivatives | TYR, AAAS, FANCD2 | MAOB 457/4885MAOA 534/4885PTPN1 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.