Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13956334 | 0.91 | HPGD (0.47) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL13971161 | 0.90 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL13956323 | 0.87 | MAOB (0.47) | ALDH1A1HPGDKDM4EMAPTGAA | |
| SCHEMBL13786667 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTGAANPSR1 | |
| SCHEMBL13956282 | 0.81 | MAOB (0.52) | ALDH1A1HPGDKDM4EMAPTGAA | |
| SCHEMBL13956302 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL13786603 | 0.77 | MAOB (0.53) | ALDH1A1HPGDHSD17B10MAPTGAA | |
| SCHEMBL14221547 | 0.75 | GAA (0.47) | ALDH1A1KDM4EMAPTGAANPSR1 | |
| SCHEMBL13786439 | 0.73 | MAOB (0.46) | ALDH1A1HPGDKDM4EMAPTGAA | |
| SCHEMBL14204715 | 0.73 | DHODH (0.43) | ALDH1A1MAPTGAALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005321-A1 | Phenylazetidinone Derivatives | MICROBIA, INC. (US) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005321-A1 | Phenylazetidinone Derivatives | TYR, AAAS, FANCD2 | ALDH1A1 366/4885HPGD 57/4885KDM4E 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.