Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 20/20 | 0.69 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrobetulonic Acid SCHEMBL3276418 | 0.90 | GPBAR1 (0.71) | GPBAR1PRKCDLMNANT5ESMN1; SMN2 | |
| Dihydrobetulonic Acid SCHEMBL10061167 | 0.90 | GPBAR1 (0.71) | GPBAR1PRKCDLMNANT5ESMN1; SMN2 | |
| Dihydrobetulonic Acid SCHEMBL14414141 | 0.90 | GPBAR1 (0.71) | GPBAR1PRKCDLMNANT5ESMN1; SMN2 | |
| Dihydrobetulonic Acid SCHEMBL13908784 | 0.90 | GPBAR1 (0.71) | GPBAR1PRKCDLMNANT5ESMN1; SMN2 | |
| SCHEMBL13301977 | 0.83 | GPBAR1 (0.65) | GPBAR1PRKCDLMNANT5ESMN1; SMN2 | |
| SCHEMBL14134447 | 0.83 | GPBAR1 (0.65) | GPBAR1PRKCDLMNANT5ESMN1; SMN2 | |
| SCHEMBL23284050 | 0.82 | GPBAR1 (0.73) | GPBAR1PRKCD | |
| SCHEMBL17281331 | 0.82 | GPBAR1 (0.83) | GPBAR1PRKCD | |
| SCHEMBL13748109 | 0.82 | GPBAR1 (0.64) | GPBAR1PRKCD | |
| Dihydrobetulinic Acid SCHEMBL14071702 | 0.82 | GPBAR1 (1.00) | GPBAR1PRKCDLMNANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131337-B1 | NOVEL BETULINIC ACID DERIVATIVES, PROCESSES FOR PREPARING SUCH DERIVATIVES AND ITS USE AS CANCER GROWTH INHIBITORS | DABUR PHARMA LTD (IN) | 2009-01-14 | — | — | EP | disclosed |