Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 7/20 | 0.49 |
| ▸ | CA2 | P00918 | 7/20 | 0.49 |
| ▸ | CA9 | Q16790 | 7/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339218 | 0.84 | AKR1B1 (0.46) | CA2ALDH1A1 | |
| SCHEMBL310967 | 0.83 | CA12 (0.45) | MAPK8CA12CA1CA2CA9 | |
| SCHEMBL31291159 | 0.83 | CA12 (0.45) | MAPK8CA12CA1CA2CA9 | |
| SCHEMBL1449282 | 0.82 | CA12 (0.47) | MAPK8CA12CA1CA2CA9 | |
| SCHEMBL1778391 | 0.82 | CA12 (0.47) | MAPK8CA12CA1CA2CA9 | |
| SCHEMBL30041815 | 0.82 | CA2 (0.45) | MAPK8CA12CA1CA2CA9 | |
| Benzene SCHEMBL15265833 | 0.81 | AKR1B1 (0.50) | CA2 | |
| SCHEMBL17802717 | 0.80 | GAA (0.38) | MAPK8CA12CA1CA2CA9 | |
| SCHEMBL13750888 | 0.80 | GAA (0.38) | MAPK8CA12CA1CA2CA9 | |
| SCHEMBL6963978 | 0.80 | CA12 (0.46) | MAPK8CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104817484-B | 2-indolone derivatives and preparation method thereof | 安徽师范大学 | 2017-04-19 | — | — | CN | claimed |
| CN-104817485-B | Isoindigo derivative and preparation method thereof | 安徽师范大学 | 2017-04-19 | — | — | CN | claimed |
| US-20120190680-A1 | Heteroaryl Amide Analogues | H. LUNDBECK A/S (DK) | 2012-07-26 | — | — | US | claimed |
| EP-2185560-A1 | HETEROARYL AMIDE ANALOGUES | H. Lundbeck A/S (DK) | 2010-05-19 | — | — | EP | claimed |
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | claimed |
| WO-2009023623-A1 | HETEROARYL AMIDE ANALOGUES | H, LUNDBECK A/S (DK) | 2009-02-19 | — | — | WO | claimed |
| CN-101307143-A | Organic-inorganic composite lamellar compound with regular arrangement bromium and method for preparing same | UNIV SHANGHAI (CN) | 2008-11-19 | — | — | CN | claimed |
| US-3943152-A | Method for preparing azines | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-03-09 | — | — | US | claimed |
| EP-4618974-A1 | OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-113462278-B | Varnish composition, method for producing polyimide resin, and additive | 东京应化工业株式会社 | 2024-06-07 | — | — | CN | disclosed |
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024107615-A1 | OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME LLC (US) | 2024-05-23 | — | — | WO | disclosed |
| CN-117003744-A | Five-membered and six-membered compound, intermediate, preparation method, composition and application | 厦门市博瑞来医药科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-113462278-A | Varnish composition, method for producing polyimide resin, and additive | 东京应化工业株式会社 | 2021-10-01 | — | — | CN | disclosed |
| WO-1998024756-A1 | PHENYL ACETAMIDES AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |
| US-5039673-A | Anticoagulants, bronchodilators, vasodilators | GLAXO GROUP LIMITED (GB) | 1991-08-13 | — | — | US | disclosed |
| EP-0296802-A1 | Aminocyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1988-12-28 | — | — | EP | disclosed |
| EP-0257768-A1 | 2-Isopropyl-2-phenyl-5-(N-methyl-2-phenylethylamino)-valeronitrile derivatives and processes for their preparation | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1988-03-02 | — | — | EP | disclosed |
| EP-0011858-A1 | Radioiodine containing amines, their preparation and their use as brain imaging agents | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-06-11 | — | — | EP | disclosed |
| US-3943152-A | Method for preparing azines | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190680-A1 | Heteroaryl Amide Analogues | P2RX3, P2RX2, ADORA2A | MAPK8 1789/4885CA12 4836/4885CA1 4547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.