Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD74 | P04233 | 2/20 | 0.64 |
| ▸ | MIF | P14174 | 2/20 | 0.64 |
| ▸ | IDO1 | P14902 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CBX7 | O95931 | 6/20 | 0.55 |
| ▸ | CDYL | Q9Y232 | 6/20 | 0.55 |
| ▸ | CDYL2 | Q8N8U2 | 5/20 | 0.55 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13367744 | 0.81 | MIF (0.66) | CD74MIFKMT2APOLBMEN1 | |
| SCHEMBL6425871 | 0.80 | IDO1 (0.69) | IDO1 | |
| SCHEMBL616373 | 0.80 | SIGMAR1 (0.53) | CD74MIFIDO1KMT2ACBX7 | |
| SCHEMBL8180452 | 0.80 | MIF (0.63) | CD74MIFIDO1KMT2APOLB | |
| SCHEMBL30336433 | 0.80 | SIGMAR1 (0.53) | CD74MIFIDO1KMT2ACBX7 | |
| SCHEMBL2149143 | 0.78 | CD74 (0.62) | CD74MIFIDO1KMT2ACBX7 | |
| SCHEMBL18805702 | 0.78 | MIF (1.00) | CD74MIFIDO1KMT2ACBX7 | |
| SCHEMBL5544872 | 0.78 | CD74 (0.54) | CD74MIFIDO1KMT2ACBX7 | |
| SCHEMBL14615630 | 0.78 | KMO (0.67) | CD74MIFCBX7CDYLCDYL2 | |
| SCHEMBL13164129 | 0.78 | MIF (0.50) | CD74MIFIDO1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009012421-A1 | CYCLIC AMINE SUBSTITUTED PYRIMIDINEDIAMINES AS PKC INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |