Baicalein

Baicalein

SCHEMBL139617

O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 6/20 1.00
PTPRS Q13332 6/20 1.00
CREB1 P16220 6/20 1.00
CYP1A1 P04798 4/20 1.00
KMT2A Q03164 4/20 1.00
CYP1B1 Q16678 4/20 1.00
FTO Q9C0B1 4/20 1.00
GABRP O00591 3/20 1.00
GABRD O14764 3/20 1.00
GABRA1 P14867 3/20 1.00
GABRB1 P18505 3/20 1.00
GABRG2 P18507 3/20 1.00
GABRB3 P28472 3/20 1.00
GABRA5 P31644 3/20 1.00
GABRA3 P34903 3/20 1.00
GABRA2 P47869 3/20 1.00
GABRB2 P47870 3/20 1.00
GABRA4 P48169 3/20 1.00
GABRE P78334 3/20 1.00
GABRA6 Q16445 3/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Baicalein SCHEMBL5695785 1.00 ABCB1 (1.00) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL29385549 1.00 ABCB1 (1.00) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28826034 0.98 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28372093 0.98 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL2420136 0.98 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28198926 0.98 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28630648 0.98 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28206740 0.98 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28087999 0.98 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
SCHEMBL8250407 0.97 ABCB1 (0.94) ABCB1PTPRSCREB1CYP1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11554 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848462-B1 BAICALEIN- AND SCUTELLAREIN-SYNTHESIZING MICROORGANISM, PREPARATION METHOD, AND APPLICATIONS THEREOF CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2026-05-27 EP claimed
CN-122075558-A Application of semen oroxyli total flavonoids in preparing medicament for treating uveitis 2026-05-26 CN claimed
CN-118901737-B Antibacterial agent containing negundo chastetree extract and application thereof 重庆安赛搏新材料技术有限公司 2026-05-19 CN claimed
CN-122056935-A Application of semen oroxyli total flavone in preparing medicament for treating atopic dermatitis 南方医科大学 2026-05-19 CN claimed
CN-122031457-A Application of baicalein in preventing and treating iron death induced by porcine reproductive and respiratory syndrome 华南农业大学 2026-05-15 CN claimed
EP-4739300-A1 MODULATORS OF IRON METABOLISM FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION SORBONNE UNIVERSITE (FR) 2026-05-13 EP claimed
US-20260108451-A1 COMPOSITIONS FOR THE MANAGEMENT OF HIRSUTISM MAJEED ANJU (IN) 2026-04-23 US claimed
EP-4728879-A1 MEMORY DISORDER AMELIORATING AGENT National University Corporation Kobe University (JP) 2026-04-22 EP claimed
US-20260103663-A1 ANTIMICROBIAL MATERIALS AND NANOPARTICLES AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2026-04-16 US claimed
US-20260096977-A1 Compositions Containing a UV-Absorbing System Including Physical UV-Attenuating Material and Flavone L'OREAL (FR) 2026-04-09 US claimed
EP-0621895-A1 INHIBITION OF THE FORMATION OR ACTIVITY OF HUMAN LEUKOCYTE 12-LIPOXYGENASE PATHWAY CITY OF HOPE (US) 1994-11-02 EP claimed
WO-1994005777-A1 INHIBITION OF THE FORMATION OR ACTIVITY OF HUMAN LEUKOCYTE 12-LIPOXYGENASE PATHWAY CITY OF HOPE (US) 1994-03-17 WO claimed
EP-0348509-B1 ANTI-RETROVIRAL DRUG TSUMURA & CO. (JP) 1993-03-24 EP claimed
EP-0496349-A1 Coating solution for preventing adhesion of polymer scale and method for its use SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-07-29 EP claimed
EP-0332478-B1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECH (FR) 1992-03-25 EP claimed
EP-0348509-A1 ANTI-RETROVIRAL DRUG TSUMURA & CO. (JP) 1990-01-03 EP claimed
CN-1037834-A With hydration lamellar fat mutually or liposome is the compositions of main component, wherein contain the Radix Scutellariae extract or contain wherein a kind of component at least, and cosmetics or medicament, especially skin is had antiallergic, the compositions of antiinflammatory or defying age performance LVMH RECH (FR) 1989-12-13 CN claimed
WO-1989008447-A1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECHERCHE (FR) 1989-09-21 WO claimed
EP-0332478-A1 Liposomes containing Scutellaria extracts LVMH RECHERCHE (FR) 1989-09-13 EP claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed