Baicalein

Baicalein

SCHEMBL28206740

O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12.[AlH3]

nearest known ligand 0.97

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 6/20 0.97
PTPRS Q13332 6/20 0.97
CREB1 P16220 6/20 0.97
CYP1A1 P04798 4/20 0.97
KMT2A Q03164 4/20 0.97
CYP1B1 Q16678 4/20 0.97
FTO Q9C0B1 4/20 0.97
GABRP O00591 3/20 0.97
GABRD O14764 3/20 0.97
GABRA1 P14867 3/20 0.97
GABRB1 P18505 3/20 0.97
GABRG2 P18507 3/20 0.97
GABRB3 P28472 3/20 0.97
GABRA5 P31644 3/20 0.97
GABRA3 P34903 3/20 0.97
GABRA2 P47869 3/20 0.97
GABRB2 P47870 3/20 0.97
GABRA4 P48169 3/20 0.97
GABRE P78334 3/20 0.97
GABRA6 Q16445 3/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Baicalein SCHEMBL5695785 0.98 ABCB1 (1.00) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL139617 0.98 ABCB1 (1.00) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL29385549 0.98 ABCB1 (1.00) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28630648 0.97 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28372093 0.97 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL2420136 0.97 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28087999 0.97 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28826034 0.97 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
Baicalein SCHEMBL28198926 0.97 ABCB1 (0.97) ABCB1PTPRSCREB1CYP1A1KMT2A
SCHEMBL8250407 0.95 ABCB1 (0.94) ABCB1PTPRSCREB1CYP1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107721962-A A kind of preparation method of baicalein aluminium complex and its preparation 河南牧翔动物药业有限公司 2018-02-23 CN claimed
CN-115326984-B Method for measuring content of baicalin metal complex by HPLC (high Performance liquid chromatography) 武汉轻工大学 2024-04-09 CN disclosed
CN-115326984-A Method for measuring content of baicalin metal complex by HPLC method 武汉轻工大学 2022-11-11 CN disclosed
CN-113621530-A Genetic engineering yeast for producing wogonin compounds, and construction method and application thereof 华东理工大学 2021-11-09 CN disclosed
CN-111440734-B Genetic engineering yeast for producing baicalein compounds, and construction method and application thereof 华东理工大学 2021-08-17 CN disclosed
CN-111000896-A Method for preparing baicalein metal complex by ore coagulation method and preparation thereof 武汉回盛生物科技股份有限公司 2020-04-14 CN disclosed
CN-106667915-B It is a kind of for treating the scutelloside aluminium dry suspensoid agent of grice diarrhoea 武汉轻工大学 2019-09-13 CN disclosed
CN-109288854-A Baicalin composition, baicalin capsule and preparation method thereof 东莞市金美济药业有限公司 2019-02-01 CN disclosed
CN-105168156-B A kind of Scullcap total-flavonoid dispersible tablet and its manufacturing method 浙江医药高等专科学校 2019-01-29 CN disclosed
CN-107721962-A A kind of preparation method of baicalein aluminium complex and its preparation 河南牧翔动物药业有限公司 2018-02-23 CN disclosed
CN-107721962-A A kind of preparation method of baicalein aluminium complex and its preparation 河南牧翔动物药业有限公司 2018-02-23 CN disclosed
CN-107721962-A A kind of preparation method of baicalein aluminium complex and its preparation 河南牧翔动物药业有限公司 2018-02-23 CN disclosed