Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | WDR5 | P61964 | 6/20 | 0.33 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987826 | 0.85 | PDE5A (0.33) | KMT2APDE5AOPRD1APLNRNPC1 | |
| SCHEMBL3987706 | 0.85 | EDNRA (0.36) | KMT2AOPRD1APLNRALDH1A1 | |
| SCHEMBL3985261 | 0.83 | PDE5A (0.36) | MAPTKMT2APDE5AALDH1A1 | |
| SCHEMBL3988500 | 0.82 | MAPK1 (0.34) | MAPTKMT2APDE5AAPLNRALDH1A1 | |
| SCHEMBL3990250 | 0.82 | DRD4 (0.38) | MAPTPDE5AALDH1A1 | |
| SCHEMBL3987544 | 0.82 | PTGS2 (0.39) | MAPTKMT2AALDH1A1 | |
| SCHEMBL3988700 | 0.82 | OPRD1 (0.36) | MAPTKMT2APDE5AOPRD1ALDH1A1 | |
| SCHEMBL3985430 | 0.81 | PDE1A (0.34) | KMT2ASMN1; SMN2PDE5AOPRD1 | |
| SCHEMBL3985186 | 0.81 | PDE1A (0.34) | KMT2ASMN1; SMN2PDE5AOPRD1ALDH1A1 | |
| SCHEMBL3988630 | 0.81 | HCRTR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473790-B2 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | PFIZER INC. (US) | 2009-01-06 | — | — | US | disclosed |