Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.37 |
| ▸ | KDM5A | P29375 | 6/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12793200 | 0.86 | EPHX2 (0.36) | ALDH1A1EPHX2CNR1NPC1SMN1; SMN2 | |
| SCHEMBL22021691 | 0.85 | EPHX2 (0.50) | ALDH1A1EPHX2CNR1CES2CES1 | |
| SCHEMBL20673423 | 0.84 | ALDH1A1 (0.62) | ALDH1A1EPHX2CNR1NPC1SMN1; SMN2 | |
| SCHEMBL22166531 | 0.84 | EPHX2 (0.53) | ALDH1A1EPHX2CNR1CES2CES1 | |
| SCHEMBL22166535 | 0.84 | EPHX2 (0.53) | ALDH1A1EPHX2CNR1CES2CES1 | |
| SCHEMBL22021679 | 0.82 | EPHX2 (0.36) | ALDH1A1EPHX2CNR1ACHEBCHE | |
| SCHEMBL13773023 | 0.82 | EPHX2 (0.62) | ALDH1A1EPHX2CNR1NPC1SMN1; SMN2 | |
| SCHEMBL7940018 | 0.82 | ALDH1A1 (0.65) | ALDH1A1EPHX2CNR1NPC1SMN1; SMN2 | |
| SCHEMBL14045500 | 0.80 | EPHX2 (0.65) | ALDH1A1EPHX2CNR1ACHEBCHE | |
| SCHEMBL21710075 | 0.80 | ALDH1A1 (0.62) | ALDH1A1EPHX2CNR1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023926-A1 | Trityl Derivatives for Enhancing Mass Spectrometry | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023926-A1 | Trityl Derivatives for Enhancing Mass Spectrometry | F3, TBCA, GYPA | ALDH1A1 1102/4885EPHX2 1027/4885CNR1 4572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.