Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM5A | P29375 | 5/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.40 |
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22166535 | 0.98 | EPHX2 (0.53) | EPHX2CNR1ALDH1A1KDM5AKDM4C | |
| SCHEMBL22166531 | 0.98 | EPHX2 (0.53) | EPHX2CNR1ALDH1A1KDM5AKDM4C | |
| SCHEMBL22021680 | 0.87 | EPHX2 (0.41) | EPHX2KDM5AKDM4CPHF8 | |
| SCHEMBL22021658 | 0.87 | EPHX2 (0.41) | EPHX2KDM5AKDM4CPHF8 | |
| SCHEMBL22021685 | 0.87 | EPHX2 (0.41) | EPHX2KDM5AKDM4CPHF8 | |
| SCHEMBL22021679 | 0.86 | EPHX2 (0.36) | EPHX2CNR1ALDH1A1KDM5AKDM4C | |
| SCHEMBL21376559 | 0.86 | EPHX2 (0.36) | EPHX2CNR1ALDH1A1CES2CES1 | |
| SCHEMBL13964304 | 0.85 | ALDH1A1 (0.50) | EPHX2CNR1ALDH1A1KDM5AKDM4C | |
| SCHEMBL21456131 | 0.84 | CYP4F2 (0.42) | EPHX2CNR1KDM5AKDM4CPHF8 | |
| SCHEMBL22021683 | 0.82 | NAMPT (0.32) | EPHX2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157078-A1 | NOVEL COMPOUNDS HAVING ESTROGEN RECEPTOR ALPHA DEGRADATION ACTIVITY AND USES THEREOF | ACCUTAR BIOTECHNOLOGY INC. (US) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157078-A1 | NOVEL COMPOUNDS HAVING ESTROGEN RECEPTOR ALPHA DEGRADATION ACTIVITY AND USES THEREOF | ESR2, ESRRG, ESR1 | EPHX2 951/4885CNR1 495/4885ALDH1A1 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.