Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 15/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | TOP1 | P11387 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | COMT | P21964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13965873 | 0.95 | PDK2 (0.36) | PDK2TOP1 | |
| SCHEMBL13965872 | 0.95 | TOP1 (0.33) | PDK2TOP1 | |
| SCHEMBL13965929 | 0.93 | PDK2 (0.31) | PDK2 | |
| SCHEMBL13965959 | 0.91 | TOP1 (0.32) | PDK2TOP1 | |
| SCHEMBL13965890 | 0.90 | KDM4E (0.34) | KDM4E | |
| SCHEMBL13965949 | 0.90 | KDM4E (0.35) | KDM4E | |
| SCHEMBL13965868 | 0.90 | PGR (0.34) | PDK2KDM4E | |
| SCHEMBL13965879 | 0.89 | PDK2 (0.41) | PDK2 | |
| SCHEMBL13965874 | 0.88 | PGR (0.31) | PDK2 | |
| SCHEMBL13965941 | 0.88 | RXFP1 (0.32) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120292603-A1 | Heterocyclic compound, organic light-emitting device including the heterocyclic compound, and flat display device including the organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2012-11-22 | — | — | US | disclosed |
| US-20120292603-A1 | Heterocyclic compound, organic light-emitting device including the heterocyclic compound, and flat display device including the organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120292603-A1 | Heterocyclic compound, organic light-emitting device including the heterocyclic compound, and flat display device including the organic light-emitting device | DDT, SUN2, CYP1B1 | PDK2 337/4885AR 1960/4885TOP1 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.