Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13965868 | 0.93 | PGR (0.34) | KDM4EL3MBTL1ATMPGRPDE4A | |
| SCHEMBL13965872 | 0.91 | TOP1 (0.33) | — | |
| SCHEMBL13965890 | 0.91 | KDM4E (0.34) | KDM4EL3MBTL1ATMPDE4APDE4B | |
| SCHEMBL13965941 | 0.91 | RXFP1 (0.32) | GSK3BPDE10A | |
| SCHEMBL13965893 | 0.90 | PDK2 (0.35) | KDM4E | |
| SCHEMBL13965883 | 0.88 | — | — | |
| SCHEMBL13965871 | 0.88 | MAPK10 (0.33) | KDM4EL3MBTL1CCR1CCR8 | |
| SCHEMBL13965894 | 0.88 | KDM4E (0.32) | KDM4EL3MBTL1ATM | |
| SCHEMBL13965959 | 0.87 | TOP1 (0.32) | — | |
| SCHEMBL17245623 | 0.87 | KDM4E (0.43) | KDM4EL3MBTL1ATMPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120292603-A1 | Heterocyclic compound, organic light-emitting device including the heterocyclic compound, and flat display device including the organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2012-11-22 | — | — | US | disclosed |
| US-20120292603-A1 | Heterocyclic compound, organic light-emitting device including the heterocyclic compound, and flat display device including the organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120292603-A1 | Heterocyclic compound, organic light-emitting device including the heterocyclic compound, and flat display device including the organic light-emitting device | DDT, SUN2, CYP1B1 | KDM4E 3176/4885L3MBTL1 2054/4885ATM 2674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.