Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.61 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.61 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.61 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13975624 | 1.00 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBSLC29A1 | |
| SCHEMBL17371116 | 1.00 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBSLC29A1 | |
| SCHEMBL21139430 | 1.00 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBSLC29A1 | |
| SCHEMBL20435006 | 0.96 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBSLC29A1 | |
| SCHEMBL26292145 | 0.96 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBSLC29A1 | |
| SCHEMBL20435009 | 0.96 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBSLC29A1 | |
| SCHEMBL26292390 | 0.92 | PI4KA (0.60) | PI4KAPI4K2BPI4K2API4KBSLC29A1 | |
| SCHEMBL13966415 | 0.92 | CCNB2 (0.52) | PI4KAPI4K2BPI4K2API4KBSLC29A1 | |
| SCHEMBL13238334 | 0.91 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBSLC29A1 | |
| SCHEMBL20434974 | 0.90 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753432-B2 | Compound with analgesic effect for use in prevention and treatment of pain | ACADEMIA SINICA (TW) | 2023-09-12 | — | — | US | disclosed |
| US-20150374737-A1 | Dual-Action Compounds Targeting Adenosine A2A Receptor and Adenosine Transporter for Prevention and Treatment of Neurodegenerative Diseases | ACADEMIA SINICA (TW) | 2015-12-31 | — | — | US | disclosed |
| US-20120295863-A1 | Dual-Action Compounds Targeting Adenosine A2A Receptor and Adenosine Transporter for Prevention and Treatment of Neurodegenerative Diseases | ACADEMIA SINICA (TW) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150374737-A1 | Dual-Action Compounds Targeting Adenosine A2A Receptor and Adenosine Transporter for Prevention and Treatment of Neurodegenerative Diseases | ADORA2A, ADORA1, ADORA3 | PI4KA 2167/4885PI4K2B 2225/4885PI4K2A 1699/4885 |
| US-11753432-B2 | Compound with analgesic effect for use in prevention and treatment of pain | ADORA2B, ADORA1, ADORA3 | PI4KA 3007/4885PI4K2B 3300/4885PI4K2A 2830/4885 |
| US-20120295863-A1 | Dual-Action Compounds Targeting Adenosine A2A Receptor and Adenosine Transporter for Prevention and Treatment of Neurodegenerative Diseases | ADORA2A, ADORA1, ADORA3 | PI4KA 2167/4885PI4K2B 2225/4885PI4K2A 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.