Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 4/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13968642 | 1.00 | KDM4E (0.42) | KDM4EATML3MBTL1TSPOPTGER4 | |
| SCHEMBL13968599 | 1.00 | KDM4E (0.42) | KDM4EATML3MBTL1TSPOPTGER4 | |
| SCHEMBL13968602 | 1.00 | KDM4E (0.42) | KDM4EATML3MBTL1TSPOPTGER4 | |
| SCHEMBL16985962 | 0.97 | KDM4E (0.39) | KDM4EATML3MBTL1TSPOPTGER4 | |
| SCHEMBL19383185 | 0.97 | KDM4E (0.38) | KDM4EATML3MBTL1TSPOPTGER4 | |
| SCHEMBL13125995 | 0.96 | L3MBTL1 (0.45) | KDM4EATML3MBTL1TSPOPTGER4 | |
| SCHEMBL19383181 | 0.95 | L3MBTL1 (0.44) | KDM4EATML3MBTL1TSPOPTGER4 | |
| SCHEMBL13968692 | 0.95 | L3MBTL1 (0.44) | KDM4EATML3MBTL1TSPOPTGER4 | |
| SCHEMBL19533763 | 0.95 | L3MBTL1 (0.44) | KDM4EATML3MBTL1TSPORXRA | |
| SCHEMBL19533760 | 0.95 | L3MBTL1 (0.44) | KDM4EATML3MBTL1TSPORXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246441-B2 | Aromatic amine derivative, and organic electroluminescent element | IDEMITSU KOSAN CO., LTD. (JP) | 2019-04-02 | — | — | US | disclosed |
| US-20120292606-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-22 | — | — | US | disclosed |
| US-20120292606-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246441-B2 | Aromatic amine derivative, and organic electroluminescent element | MAOB, MAOA, NAT1 | KDM4E 433/4885ATM 696/4885L3MBTL1 1183/4885 |
| US-20120292606-A1 | AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT | MAOB, MAOA, NAT1 | KDM4E 433/4885ATM 696/4885L3MBTL1 1183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.