Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.50 |
| ▸ | ALB | P02768 | 2/20 | 0.47 |
| ▸ | HTRA2 | O43464 | 6/20 | 0.42 |
| ▸ | HTRA1 | Q92743 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13678656 | 0.94 | FOLH1 (0.53) | FOLH1ALBHTRA2HTRA1CA9 | |
| SCHEMBL9906258 | 0.93 | FOLH1 (0.52) | FOLH1ALBHTRA2HTRA1CA9 | |
| SCHEMBL13678635 | 0.92 | FOLH1 (0.51) | FOLH1ALBHTRA2HTRA1CA9 | |
| SCHEMBL1688099 | 0.91 | FOLH1 (0.51) | FOLH1ALBCA9ESR1USP2 | |
| SCHEMBL9906256 | 0.91 | FOLH1 (0.57) | FOLH1ALBHTRA2HTRA1ESR1 | |
| SCHEMBL13678631 | 0.89 | FOLH1 (0.48) | FOLH1ALBHTRA2HTRA1CA9 | |
| SCHEMBL9906325 | 0.89 | FOLH1 (0.54) | FOLH1ALBHTRA2HTRA1CA9 | |
| SCHEMBL9906321 | 0.88 | FOLH1 (0.55) | FOLH1ALBHTRA2HTRA1CA9 | |
| SCHEMBL9906326 | 0.87 | FOLH1 (0.56) | FOLH1ALBCA9ESR1USP2 | |
| SCHEMBL9906226 | 0.87 | ALB (0.49) | FOLH1ALBHTRA2HTRA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090011432-A1 | Detecting and Profiling Molecular Complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-7402397-B2 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2008-07-22 | — | — | US | disclosed |