SCHEMBL9906325

SCHEMBL9906325

O=C(CSCCC(=O)ON1C(=O)CCC1=O)NCCCCNC(=O)c1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 2/20 0.54
▸ ALB P02768 2/20 0.53
▸ SLC5A2 P31639 3/20 0.48
▸ ESR1 P03372 1/20 0.47
▸ USP2 O75604 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ CA9 Q16790 3/20 0.45
▸ CA12 O43570 2/20 0.44
▸ CA1 P00915 2/20 0.44
▸ CA2 P00918 2/20 0.44
▸ HTRA2 O43464 1/20 0.44
▸ HTRA1 Q92743 1/20 0.44
▸ AVPR2 P30518 1/20 0.44
▸ OXTR P30559 1/20 0.44
▸ AVPR1A P37288 1/20 0.44
▸ HAVCR2 Q8TDQ0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9906321 0.99 FOLH1 (0.55) FOLH1ALBSLC5A2ESR1USP2
SCHEMBL1688099 0.97 FOLH1 (0.51) FOLH1ALBSLC5A2ESR1USP2
SCHEMBL9906327 0.96 FOLH1 (0.52) FOLH1ALBSLC5A2ESR1USP2
SCHEMBL9906261 0.95 ALB (0.52) FOLH1ALBSLC5A2HTRA2HTRA1
SCHEMBL9906326 0.94 FOLH1 (0.56) FOLH1ALBSLC5A2ESR1USP2
SCHEMBL9906226 0.93 ALB (0.49) FOLH1ALBESR1USP2L3MBTL1
SCHEMBL13678665 0.92 ESR1 (0.52) FOLH1ALBSLC5A2ESR1USP2
SCHEMBL14427154 0.92 FOLH1 (0.45) FOLH1ALBSLC5A2ESR1HTRA2
SCHEMBL13678640 0.92 ALB (0.53) FOLH1ALBSLC5A2ESR1USP2
SCHEMBL9906192 0.91 ALB (0.49) FOLH1ALBSLC5A2ESR1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673399-B1 DETECTING AND PROFILING MOLECULAR COMPLEXES MONOGRAM BIOSCIENCES INC (US) 2017-04-05 — — EP disclosed
US-8198031-B2 Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening MONOGRAM BIOSCIENCES, INC. (US) 2012-06-12 — — US disclosed
EP-1540347-B1 DETECTING RECEPTOR OLIGOMERIZATION ACLARA BIOSCIENCES INC (US) 2009-09-09 — — EP disclosed
US-20090173631-A1 Single Cell Analysis of Membrane Molecules ACLARA BIOSCIENCES, INC. 2009-07-09 — — US disclosed
US-20090011432-A1 Detecting and Profiling Molecular Complexes MONOGRAM BIOSCIENCES, INC. (US) 2009-01-08 — — US disclosed
US-20080233602-A1 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. 2008-09-25 — — US disclosed
US-7402397-B2 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. (US) 2008-07-22 — — US disclosed
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