Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.57 |
| ▸ | ALB | P02768 | 2/20 | 0.50 |
| ▸ | HTRA2 | O43464 | 8/20 | 0.46 |
| ▸ | HTRA1 | Q92743 | 8/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13678656 | 0.97 | FOLH1 (0.53) | FOLH1ALBHTRA2HTRA1SLC5A2 | |
| SCHEMBL9906258 | 0.96 | FOLH1 (0.52) | FOLH1ALBHTRA2HTRA1SLC5A2 | |
| SCHEMBL9906321 | 0.92 | FOLH1 (0.55) | FOLH1ALBHTRA2HTRA1SLC5A2 | |
| SCHEMBL9906325 | 0.91 | FOLH1 (0.54) | FOLH1ALBHTRA2HTRA1SLC5A2 | |
| SCHEMBL13969976 | 0.91 | FOLH1 (0.50) | FOLH1ALBHTRA2HTRA1SLC5A2 | |
| SCHEMBL13678635 | 0.90 | FOLH1 (0.51) | FOLH1ALBHTRA2HTRA1SLC5A2 | |
| SCHEMBL14427794 | 0.89 | FOLH1 (0.44) | FOLH1ALBHTRA2HTRA1ESR1 | |
| SCHEMBL1688099 | 0.89 | FOLH1 (0.51) | FOLH1ALBSLC5A2ESR1 | |
| SCHEMBL13678645 | 0.88 | ALB (0.45) | FOLH1ALBHTRA2HTRA1ESR1 | |
| SCHEMBL9906261 | 0.88 | ALB (0.52) | FOLH1ALBHTRA2HTRA1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673399-B1 | DETECTING AND PROFILING MOLECULAR COMPLEXES | MONOGRAM BIOSCIENCES INC (US) | 2017-04-05 | — | — | EP | disclosed |
| US-8198031-B2 | Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening | MONOGRAM BIOSCIENCES, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| EP-1540347-B1 | DETECTING RECEPTOR OLIGOMERIZATION | ACLARA BIOSCIENCES INC (US) | 2009-09-09 | — | — | EP | disclosed |
| US-20090011432-A1 | Detecting and Profiling Molecular Complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-20080233602-A1 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. | 2008-09-25 | — | — | US | disclosed |
| US-7402397-B2 | Detecting and profiling molecular complexes | MONOGRAM BIOSCIENCES, INC. (US) | 2008-07-22 | — | — | US | disclosed |